United welcome back James Henry, Jack Stevens, Sam Long and Ciaron Brown after injury and illness but are still without Elliott Moore, Marcus Browne and Sam Baldock as well as long term absentees Jamie Hanson and Alex Gorrin.
Gorrin and hanson made first appearances on the grass pitches at the Bangkok Glass Training Centre this week but neither will appear in the remaining league games.
Boss Karl Robinson must decide whether to make changes to a winning side after their 2-1 win at Shrewsbury last weekend, a win that keeps United in fourth place in the table.
Meanwhile young striker Slavi Spasov will continue his return to fitness with a loan at North Leigh.
Ipswich Boss Kieran McKenna has seen his side go unbeaten in the last nine games with eight clean sheets in the process.
“Oxford are a good team with some really strong individual players,” the Town boss told iFollow Ipswich. It’s not a surprise that they’re up there
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this season or that they have scored a lot of goals. We certainly respect them and we will go there expecting to face a brave team that likes to attack.
“Their home record is good and we will be wary of their threats, but beyond that will be the same in that we will focus on ourselves and try to make it the type of game
we want it to be. We will look to impose our style on the game, and if we do that and put in a strong performance, we have a good chance of getting the result we want.”
