It has not been the start to the season that Neil Warnock will have been hoping for after his team proved to be one of the strongest outfits in the league last season, having just missed out on the playoffs.
Middlesbrough currently sit 18th in the table and they trail Sheffield United by three points after winning just two games so far in the league.
Boro have lost their last two games, with Blackpool and Reading being able to earn three points at their expense, which is the type of form they will now be hoping to put an end to.
The last time Warnock’s men won a game was against Nottingham Forest as Onel Hernandez and Andraz Sporar were on hand to provide the goals that day, which was only the second time this season that they have kept a clean sheet.
Throughout history, neither team has dominated when it comes to this fixture, with Boro having won 41 times and the Yorkshire outfit edging the battle with 44.
That is something that Sheffield United will be eager to continue as they try to keep progressing up the table in order to get themselves in contention for promotion.
The Blades are currently just four points outside of the playoffs spots, which is a gap they will be hoping to cut down, while a defeat on Tuesday would see Middlesbrough draw level with them.
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They are unbeaten in six games at the moment in the Championship, which is something that Slavisa Jokanovic will be very pleased with, showcasing their consistency.
Sheffield United left it late to secure three points at the weekend, though, during their match with Derby County, when they had to wait for an 89th-minute penalty to gain a 1-0 win, as Billy Sharp stepped up to take on the responsibility.
The Blades will now be attempting to follow up on that performance with another victory on Tuesday, with this fixture providing them with the chance to win a trio of games consecutively in the league for the first time this season