League Two outfit Grimsby are looking to eliminate another side from a higher division after beating three League One teams to progress to the fourth round.
Plymouth Argyle, Cambridge United and Burton Albion were all dispatched in the first three rounds, before they held Luton to a draw at the end of January.
Gavan Holohan gave Grimsby the lead before Elijah Adebayo equalised from the spot, and Luton turned the game on its head with Jordan Clarke’s 66th-minute effort, however, Luton’s lead lasted less than a minute, as Harry Clifton found an equalising goal to take the tie to a replay.
Paul Hurst’s side will head into Tuesday’s game in confident mood after cruising to a 3-0 away win over Crewe Alexandra thanks to goals from debutants George Lloyd and Thomas Dickson-Peters as well as a strike from John McAtee.
Grimsby have won their last two home games, and if they can claim another home victory on Tuesday, they will progress to the fifth round of the FA Cup for the first time since the 1992-93 season.
Luton Town are enjoying a successful championship campaign, sitting in fourth place and five points clear of those chasing from just outside the playoffs.
In their most recent outing, Luton extended their unbeaten to five games in all competitions by claiming a 1-0 home victory over Stoke City thanks to a sixth-minute strike from Pelly Ruddock-Mpanzu.
Rob Edwards’s side will put their league campaign on hold as they attempt to secure a place in the FA Cup fifth round for a second straight season.
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The visitors head into the midweek contest in impressive away form after winning their last four competitive matches on their travels, scoring at least two goals in each of those victories.
If Luton can claim a cup victory on Tuesday, they will set up a meeting with their former manager Nathan Jones, who left the club to take over as Southampton boss in November
Grimsby will be unable to call upon Luton loanee McAtee, who is ineligible to face his parent club.January arrivals Mikey O’Neill and Lloyd are cup-tied after previously playing in the competition for Preston North End and
Cheltenham Town respectively.After making their debuts for the club on Saturday, Josh Emmanuel and Dickson-Peters are expected to feature in the starting lineup.As for the visitors, they are without the services of Luke Freeman,
Sonny Bradley and Henri Lansbury due to injury issues.January arrivals Jack Walton, Joe Taylor and Cody Drameh are all cup-tied, while Aston Villa loanee Marvelous Nakamba is unavailable having not signed before the initial tie.
