The Bluebirds have experienced a mixed start to their season, winning two of their opening seven games in all competitions.
Since beating Birmingham City 1-0 on August 13, Cardiff have gone on to take just two points from their next three league encounters, leaving them in 14th place ahead of the midweek contest.
A goalless draw away to West Bromwich Albion was followed by a 2-0 away defeat to Bristol City, ensuring that they are yet to win on their travels this season.
They had the chance to clinch consecutive home victories on Saturday, but had to settle for another goalless draw against a Preston North End side who have not conceded in the league this season.
Having failed to score in their last three matches, Steve Morison’s side will need to improve in the final third if they are to claim all three points on Tuesday.
Like their hosts, Luton have also struggled for wins this season, with their opening seven games in all competitions yielding one victory.
The Hatters began their Championship campaign with a four-game winless run before they beat Swansea City 2-0 to claim their first win of the season.
After goals from Allan Campbell and Carlton Morris helped Luton defeat the Swans, they had the chance to clinch back-to-back victories on Friday against Sheffield United.
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Morris gave the Hatters an early lead, but a second-half strike from Oli McBurnieensured that the spoils were shared, which leaves Nathan Jones’s side in 19th place ahead of Tuesday’s encounter.
After netting four goals in their opening six league games, Luton will hope that they score more than one goal in a game on Tuesday for only the second time in the Championship this season
Cardiff will be without the services of Joel Bagan due to a head injury, while Jamilu Collins is a long-term absentee.
Niels Nkounkou came off the bench to make his debut for the club on Saturday, and the left-back could be given his first start against Luton.
