Cambridge enter the weekend in 16th position, which leaves them seven points clear of the relegation zone.
The U’s enter Saturday’s contest off the back of a 2-0 defeat to Charlton Athletic last weekend, which frustratingly ended a run of three consecutive victories in all competitions.
A Conor Washington brace was enough to condemn Cambridge to defeat in that fixture, and Mark Bonner will know that his side will be up against it to avoid a similar result when the league leaders come to town on Saturday.
A positive start will be needed if the hosts are to trouble Rotherham, but having failed to score in the opening 15 minutes at home in the league this season, it may be unlikely that Cambridge will fly out the traps.
Although, after losing once in their last eight home games in all competitions, Bonner may be hopeful that his side can frustrate the Millers at the weekend.
Rotherham have swept past all challengers this season with the hosts unbeaten since a 4-2 defeat at home to Fleetwood Town on September 11.
Since that loss, the Millers have avoided defeats in their last 20 competitive fixtures, which has helped them obtain a two-point gap at the top of League One.https://c3601096e08b570b091763130977f817.safeframe.googlesyndication.com/safeframe/1-0-38/html/container.html?n=0
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Paul Warne’s side will make their first away trip of December full of confidence after winning consecutive home games, with the Millers scoring eight goals in those two fixtures.
A comfortable 5-1 win over Gillingham was followed by an impressive 3-1 victory last weekend against Burton Albion that came courtesy of a Freddie Ladapo brace and a Dan Barlaser strike.
Having kept five clean sheets in their last six away games, Rotherham will believe that they have the resources to overpower Cambridge on Saturday