The hosts will return to action for the first time since December 18 after their festive schedule was wiped out due to a couple of coronavirus-related postponements.
Mark Bonner’s side enter the fixture six points above the drop zone after losing to Charlton Athletic and Rotherham United in their last two outings.
In fact, their league form has been less than impressive of late, with the U’s winning just once in their last seven League One fixtures.
Draws have been the order of the day for Bonner’s men in recent home fixtures, with four of their last eight home league games finishing level.
If they are to collect at least a point on Monday, the hosts are likely to pose more of a threat in the second half, with Cambridge scoring 22 goals in the second period this season – compared to the 10 goals that they have netted in the opening 45 minutes in the league this term.
Meanwhile, Portsmouth will finally take to the field for the first time since December 11 after seeing three of their league fixtures postponed in the final month of 2021.
When they return to action on Monday, Danny Cowley’s side will look to continue their current unbeaten league run, which has seen them avoid defeat in their last nine League One games.
In their last outing, Marcus Harness and Connor Ogilvie both netted to guide Pompey to a 2-0 home victory over Morecambe.
That result saw Cowley’s men pick up their second consecutive clean sheet, and their strong defensive displays have been key in Pompey’s recent success.
They have managed to keep eight clean sheets in their last 11 competitive fixtures, and having claimed shutouts in all of their last three away matches, Pompey will believe that they can claim a positive result on Monday.