Jimmy Floyd Hasselbaink will be hoping his squad can pick up their fourth win of the season on Tuesday and respond to the recent 1-1 draw they picked up against Cheltenham Town.
Burton fought back from going a goal down on Saturday, with a strike from Lucas Akins helping his team secure a point in a fixture that saw Michael Mancienne suffer a hamstring injury.
The point was welcomed by Hasselbaink on the back of a 3-0 defeat against Cambridge United in their previous outing, which is why this cup fixture will likely be a positive distraction in a bid to get back to winning ways.
Burton have started the season well though, currently sitting just outside the playoffs in League One, being just two points behind the leaders Sunderland.
With just one defeat so far in the league, there should be no shortage of confidence, although they will be hoping for an improvement on their EFL Cup adventures which saw them knocked out in the first round against Oxford United via penalties.
In a group that also features Wycombe Wanderers and Aston Villa’s Under-21s side, both MK Dons and Burton will be hoping to start with a positive result.
Last season saw Burton crash out of the competition in the group stage, finishing third after securing just one victory, meanwhile MK Dons topped their group.
The Dons actually made it through to the quarter-finals last season in the EFL Trophy, eventually being knocked out by Sunderland who then went on to win the entire competition.
Much like Burton, MK Dons have only lost once so far in the league, having drawn twice and picked up two wins as well, one of which took place during their most recent outing.
Liam Manning’s squad head into the game following a 2-0 win against Accrington Stanley with goals coming from Mohamed Eisa and Matt O’Riley as The Dons earned their first clean sheet of the season.
Manning only took charge of the club partway through August after Russell Martin took over Swansea City, but so far it has been a great start for him, having guided the team to two wins and a draw, with only one defeat to the current league leaders Sunderland